CALCIUM CHLORIDE

Chemwatch Independent Material Safety Data Sheet

Issue Date: 17-Jul-2011

NC317TCP

CHEMWATCH 20922

Version No:5

Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION

PRODUCT NAME

CALCIUM CHLORIDE

PRODUCT USE

Used as a drying, dehydrating, desiccating agent for organic liquids, gases. Obsolescent use as refrigerant brine. Dust control for roads. De-icing fluid, freeze proofing and thawing coal, coke, stone, sand, ore. Sizing and finishing cotton fabrics; used in the paper and pulp industry. In the manufacture of fungicides. Conditioning treatment for concrete. Food Additive 509. Sequestrant in foods, firming agent in tomato canning. Anhydrous form must NOT be used as Calcium Chloride Injection, Calcium ion.

SUPPLIER

Company: Tennant Trading Pty Ltd
Address:
Level 2, 40 Yeo Street
Neutral Bay
NSW, 2089
Australia
Telephone: +61 2 9908 9100
Emergency Tel: 1800 039 008 (24 hours)
Emergency Tel: +61 3 9573 3112
Fax: +61 2 9908 9111

Section 2 - HAZARDS IDENTIFICATION

STATEMENT OF HAZARDOUS NATURE

HAZARDOUS SUBSTANCE. NON-DANGEROUS GOODS. According to NOHSC Criteria, and ADG Code.

CHEMWATCH HAZARD RATINGS

Flammability 0
Toxicity 2
Body Contact 2
Reactivity 0
Chronic 2
SCALE: Min/Nil=0 Low=1 Moderate=2 High=3 Extreme=4

 

RISK SAFETY
■ Harmful if swallowed. • Do not breathe dust.
■ Irritating to eyes. • Avoid contact with skin.
■ Repeated exposure may cause skin dryness and cracking. • Avoid contact with eyes.
■ Cumulative effects may result following exposure*. • Wear suitable protective clothing.
* (limited evidence). • Wear suitable gloves.
• Wear eye/ face protection.
• To clean the floor and all objects contaminated by this material, use water.
• Keep away from food, drink and animal feeding stuffs.
• In case of contact with eyes, rinse with plenty of water and contact Doctor or Poisons Information Centre.
• If swallowed, IMMEDIATELY contact Doctor or Poisons Information Centre (show this container or label).

 

Section 3 - COMPOSITION / INFORMATION ON INGREDIENTS

NAME CAS RN %
calcium chloride 10043-52-4 >85
commercial materials may contain up to
3% sodium chloride

Section 4 - FIRST AID MEASURES

SWALLOWED

· IF SWALLOWED, REFER FOR MEDICAL ATTENTION, WHERE POSSIBLE, WITHOUT DELAY.
· For advice, contact a Poisons Information Centre or a doctor.
· Urgent hospital treatment is likely to be needed.
· In the mean time, qualified first-aid personnel should treat the patient following observation and employing supportive measures as indicated by the patient's condition.
· If the services of a medical officer or medical doctor are readily available, the patient should be placed in his/her care and a copy of the MSDS should be provided. Further action will be the responsibility of the medical specialist.
· If medical attention is not available on the worksite or surroundings send the patient to a hospital together with a copy of the MSDS.

Where medical attention is not immediately available or where the patient is more than 15 minutes from a hospital or unless instructed otherwise:
· INDUCE vomiting with fingers down the back of the throat, ONLY IF CONSCIOUS. Lean patient forward or place on left side (head-down position, if possible) to maintain open airway and prevent aspiration.
NOTE: Wear a protective glove when inducing vomiting by mechanical means.

EYE

■ If this product comes in contact with the eyes:
· Wash out immediately with fresh running water.
· Ensure complete irrigation of the eye by keeping eyelids apart and away from eye and moving the eyelids by occasionally lifting the upper and lower lids.
· Seek medical attention without delay; if pain persists or recurs seek medical attention.
· Removal of contact lenses after an eye injury should only be undertaken by skilled personnel.

SKIN

■ If skin or hair contact occurs:
· Flush skin and hair with running water (and soap if available).
· Seek medical attention in event of irritation.

INHALED

· If fumes, aerosols or combustion products are inhaled remove from contaminated area.
· Other measures are usually unnecessary.

NOTES TO PHYSICIAN

■ for poisons (where specific treatment regime is absent):
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
BASIC TREATMENT
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
· Establish a patent airway with suction where necessary.
· Watch for signs of respiratory insufficiency and assist ventilation as necessary.
· Administer oxygen by non- rebreather mask at 10 to 15 L/min.
· Monitor and treat, where necessary, for pulmonary oedema .
· Monitor and treat, where necessary, for shock.
· Anticipate seizures .
· DO NOT use emetics. Where ingestion is suspected rinse mouth and give up to 200 ml water (5 ml/kg recommended) for dilution where patient is able to swallow, has a
strong gag reflex and does not drool.
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
ADVANCED TREATMENT
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
· Consider orotracheal or nasotracheal intubation for airway control in unconscious patient or where respiratory arrest has occurred.
· Positive- pressure ventilation using a bag- valve mask might be of use.
· Monitor and treat, where necessary, for arrhythmias.
· Start an IV D5W TKO. If signs of hypovolaemia are present use lactated Ringers solution. Fluid overload might create complications.
· Drug therapy should be considered for pulmonary oedema.
· Hypotension with signs of hypovolaemia requires the cautious administration of fluids. Fluid overload might create complications.
· Treat seizures with diazepam.
· Proparacaine hydrochloride should be used to assist eye irrigation.
BRONSTEIN, A.C. and CURRANCE, P.L.
EMERGENCY CARE FOR HAZARDOUS MATERIALS EXPOSURE: 2nd Ed. 1994.
Treat symptomatically.

Section 5 - FIRE FIGHTING MEASURES

EXTINGUISHING MEDIA

· There is no restriction on the type of extinguisher which may be used.
· Use extinguishing media suitable for surrounding area.

FIRE FIGHTING

· Alert Fire Brigade and tell them location and nature of hazard.
· Wear breathing apparatus plus protective gloves for fire only.
· Prevent, by any means available, spillage from entering drains or water courses.
· Use fire fighting procedures suitable for surrounding area.
· DO NOT approach containers suspected to be hot.
· Cool fire exposed containers with water spray from a protected location.
· If safe to do so, remove containers from path of fire.
· Equipment should be thoroughly decontaminated after use.

FIRE/EXPLOSION HAZARD

· Non combustible.
· Not considered a significant fire risk, however containers may burn.
Decomposition may produce toxic fumes of: hydrogen chloride, metal oxides.
May emit poisonous fumes.
May emit corrosive fumes.

FIRE INCOMPATIBILITY

■ None known.

HAZCHEM

None

PERSONAL PROTECTION

Glasses: Respirator:
Chemical goggles. Particulate

Section 6 - ACCIDENTAL RELEASE MEASURES

MINOR SPILLS

· Remove all ignition sources.
· Clean up all spills immediately.
· Avoid contact with skin and eyes.
· Control personal contact by using protective equipment.
· Use dry clean up procedures and avoid generating dust.
· Place in a suitable, labelled container for waste disposal.

MAJOR SPILLS

■ Moderate hazard.
· CAUTION: Advise personnel in area.
· Alert Emergency Services and tell them location and nature of hazard.
· Control personal contact by wearing protective clothing.
· Prevent, by any means available, spillage from entering drains or water courses.
· Recover product wherever possible.
· IF DRY: Use dry clean up procedures and avoid generating dust. Collect residues and place in sealed plastic
bags or other containers for disposal. IF WET: Vacuum/shovel up and place in labelled containers for
disposal.
· ALWAYS: Wash area down with large amounts of water and prevent runoff into drains.
· If contamination of drains or waterways occurs, advise Emergency Services.

 

Personal Protective Equipment advice is contained in Section 8 of the MSDS.

Section 7 - HANDLING AND STORAGE

PROCEDURE FOR HANDLING

· Avoid all personal contact, including inhalation.
· Wear protective clothing when risk of exposure occurs.
· Use in a well-ventilated area.
· Prevent concentration in hollows and sumps.
· DO NOT enter confined spaces until atmosphere has been checked.
· DO NOT allow material to contact humans, exposed food or food utensils.
· Avoid contact with incompatible materials.
· When handling, DO NOT eat, drink or smoke.
· Keep containers securely sealed when not in use.
· Avoid physical damage to containers.
· Always wash hands with soap and water after handling.
· Work clothes should be laundered separately. Launder contaminated clothing before re-use.
· Use good occupational work practice.
· Observe manufacturer's storing and handling recommendations.
· Atmosphere should be regularly checked against established exposure standards to ensure safe working conditions are maintained.

SUITABLE CONTAINER

· DO NOT use aluminium or galvanised containers.
· Polyethylene or polypropylene container.
· Check all containers are clearly labelled and free from leaks.

STORAGE INCOMPATIBILITY

■ Derivative of very electropositive metal.
Inorganic alkaline earth metal derivative.
Calcium chloride (and its hydrates):
· are incompatible with boric acid, calcium oxide, bromine trifluoride, 2-furan, percarboxylic acid
· may produce explosive hydrogen gas on contact with zinc
· catalyse exothermic polymerisation of methyl vinyl ether
· produce heat on contact with water
· attack metals

Addition of a quantity of calcium chloride to boiling water has generated heat sufficient to cause a violent steam explosion on several occasions.
· Metals and their oxides or salts may react violently with chlorine trifluoride and bromine trifluoride.
· These trifluorides are hypergolic oxidisers. They ignites on contact (without external source of heat or ignition) with recognised fuels - contact with these materials, following an ambient or slightly elevated temperature, is often violent and may produce ignition.
· The state of subdivision may affect the results.
· In presence of moisture, the material is corrosive to aluminium, zinc and tin producing highly flammable hydrogen gas.

PACKAGING MATERIAL INCOMPATIBILITIES

Chemical Name                   Container Type
Calcium Chloride                " Acetal (Delrinr)" , Aluminum, " Cast iron" , Neoprene

STORAGE REQUIREMENTS

· Material is hygroscopic, i.e. absorbs moisture from the air. Keep containers well sealed in storage.
· Store in original containers.
· Keep containers securely sealed.
· Store in a cool, dry area protected from environmental extremes.
· Store away from incompatible materials and foodstuff containers.
· Protect containers against physical damage and check regularly for leaks.
· Observe manufacturer's storing and handling recommendations
For major quantities:
· Consider storage in bunded areas - ensure storage areas are isolated from sources of community water (including stormwater, ground water, lakes and streams}.
· Ensure that accidental discharge to air or water is the subject of a contingency disaster management plan; this may require consultation with local authorities.

_____________________________________________________

SAFE STORAGE WITH OTHER CLASSIFIED CHEMICALS

_____________________________________________________

+: May be stored together
O: May be stored together with specific preventions
X: Must not be stored together

 

Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION

EXPOSURE CONTROLS

• calcium chloride: CAS:10043-52-4

 

MATERIAL DATA

CALCIUM CHLORIDE:
■ It is the goal of the ACGIH (and other Agencies) to recommend TLVs (or their equivalent) for all substances for which there is evidence of health effects at
airborne concentrations encountered in the workplace.
At this time no TLV has been established, even though this material may produce adverse health effects (as evidenced in animal experiments or clinical experience).
Airborne concentrations must be maintained as low as is practically possible and occupational exposure must be kept to a minimum.
NOTE: The ACGIH occupational exposure standard for Particles Not Otherwise Specified (P.N.O.S) does NOT apply.
Sensory irritants are chemicals that produce temporary and undesirable side- effects on the eyes, nose or throat. Historically occupational exposure standards for
these irritants have been based on observation of workers' responses to various airborne concentrations. Present day expectations require that nearly every
individual should be protected against even minor sensory irritation and exposure standards are established using uncertainty factors or safety factors of 5 to 10 or
more. On occasion animal no- observable- effect- levels (NOEL) are used to determine these limits where human results are unavailable. An additional approach,
typically used by the TLV committee (USA) in determining respiratory standards for this group of chemicals, has been to assign ceiling values (TLV C) to rapidly
acting irritants and to assign short- term exposure limits (TLV STELs) when the weight of evidence from irritation, bioaccumulation and other endpoints combine to
warrant such a limit. In contrast the MAK Commission (Germany) uses a five- category system based on intensive odour, local irritation, and elimination half- life.
However this system is being replaced to be consistent with the European Union (EU) Scientific Committee for Occupational Exposure Limits (SCOEL); this is more
closely allied to that of the USA.
OSHA (USA) concluded that exposure to sensory irritants can:
· cause inflammation
· cause increased susceptibility to other irritants and infectious agents
· lead to permanent injury or dysfunction
· permit greater absorption of hazardous substances and
· acclimate the worker to the irritant warning properties of these substances thus increasing the risk of overexposure.

 

PERSONAL PROTECTION

EYE

· Safety glasses with side shields.
· Chemical goggles.
· Contact lenses may pose a special hazard; soft contact lenses may absorb and concentrate irritants. A written policy document, describing the wearing of lens or
restrictions on use, should be created for each workplace or task. This should include a review of lens absorption and adsorption for the class of chemicals in use
and an account of injury experience. Medical and first- aid personnel should be trained in their removal and suitable equipment should be readily available. In the
event of chemical exposure, begin eye irrigation immediately and remove contact lens as soon as practicable. Lens should be removed at the first signs of eye redness
or irritation - lens should be removed in a clean environment only after workers have washed hands thoroughly. [CDC NIOSH Current Intelligence Bulletin 59], [AS/NZS
1336 or national equivalent].

HANDS/FEET

■ Suitability and durability of glove type is dependent on usage. Important factors in the selection of gloves include:
· frequency and duration of contact,
· chemical resistance of glove material,
· glove thickness and
· dexterity
Select gloves tested to a relevant standard (e.g. Europe EN 374, US F739, AS/NZS 2161.1 or national equivalent).
· When prolonged or frequently repeated contact may occur, a glove with a protection class of 5 or higher (breakthrough time greater than 240 minutes according to EN
374, AS/NZS 2161.10.1 or national equivalent) is recommended.
· When only brief contact is expected, a glove with a protection class of 3 or higher (breakthrough time greater than 60 minutes according to EN 374, AS/NZS
2161.10.1 or national equivalent) is recommended.
· Contaminated gloves should be replaced.
Gloves must only be worn on clean hands. After using gloves, hands should be washed and dried thoroughly. Application of a non- perfumed moisturiser is recommended.
Experience indicates that the following polymers are suitable as glove materials for protection against undissolved, dry solids, where abrasive particles are not
present.
· polychloroprene
· nitrile rubber
· butyl rubber
· fluorocaoutchouc
· polyvinyl chloride
Gloves should be examined for wear and/ or degradation constantly.

OTHER

· Overalls.
· P.V.C. apron.
· Barrier cream.
· Skin cleansing cream.
· Eye wash unit.

RESPIRATOR

•Particulate. (AS/NZS 1716 & 1715, EN 143:2000 & 149:2001, ANSI Z88 or national equivalent)
· Respirators may be necessary when engineering and administrative controls do not adequately prevent exposures.
· The decision to use respiratory protection should be based on professional judgment that takes into account toxicity information, exposure measurement data, and
frequency and likelihood of the worker' s exposure - ensure users are not subject to high thermal loads which may result in heat stress or distress due to personal
protective equipment (powered, positive flow, full face apparatus may be an option).
· Published occupational exposure limits, where they exist, will assist in determining the adequacy of the selected respiratory . These may be government mandated or
vendor recommended.
· Certified respirators will be useful for protecting workers from inhalation of particulates when properly selected and fit tested as part of a complete respiratory
protection program.
· Use approved positive flow mask if significant quantities of dust becomes airborne.
· Try to avoid creating dust conditions.
The local concentration of material, quantity and conditions of use determine the type of personal protective equipment required. For further information consult
site specific CHEMWATCH data (if available), or your Occupational Health and Safety Advisor.

ENGINEERING CONTROLS

■ Engineering controls are used to remove a hazard or place a barrier between the worker and the hazard. Well- designed engineering controls can be highly effective
in protecting workers and will typically be independent of worker interactions to provide this high level of protection.
The basic types of engineering controls are:
Process controls which involve changing the way a job activity or process is done to reduce the risk.
Enclosure and/or isolation of emission source which keeps a selected hazard " physically" away from the worker and ventilation that strategically " adds" and "
removes" air in the work environment. Ventilation can remove or dilute an air contaminant if designed properly. The design of a ventilation system must match the
particular process and chemical or contaminant in use.
Employers may need to use multiple types of controls to prevent employee overexposure.
· Local exhaust ventilation is required where solids are handled as powders or crystals; even when particulates are relatively large, a certain proportion will be
powdered by mutual friction.
· If in spite of local exhaust an adverse concentration of the substance in air could occur, respiratory protection should be considered.
Such protection might consist of:
(a): particle dust respirators, if necessary, combined with an absorption cartridge;
(b): filter respirators with absorption cartridge or canister of the right type;
(c): fresh- air hoods or masks.
Air contaminants generated in the workplace possess varying " escape" velocities which, in turn, determine the " capture velocities" of fresh circulating air
required to effectively remove the contaminant.
Type of Contaminant: Air Speed:
direct spray, spray painting in shallow booths, drum filling, conveyer loading, crusher dusts, gas discharge (active generation into zone of rapid air motion) 1-2.5 m/s (200-500 f/min.)
grinding, abrasive blasting, tumbling, high speed wheel generated dusts (released at high initial velocity into zone of very high rapid air motion). 2.5-10 m/s (500-2000 f/min.)
Within each range the appropriate value depends on:
Lower end of the range Upper end of the range
1: Room air currents minimal or favourable to capture 1: Disturbing room air currents
2: Contaminants of low toxicity or of nuisance value only. 2: Contaminants of high toxicity
3: Intermittent, low production. 3: High production, heavy use
4: Large hood or large air mass in motion 4: Small hood-local control only
Simple theory shows that air velocity falls rapidly with distance away from the opening of a simple extraction pipe. Velocity generally decreases with the square of distance from the extraction point (in simple cases). Therefore the air speed at the extraction point should be adjusted, accordingly, after reference to distance from the contaminating source. The air velocity at the extraction fan, for example, should be a minimum of 4- 10 m/s (800- 2000 f/min) for extraction of crusher dusts generated 2 metres distant from the extraction point. Other mechanical considerations, producing performance deficits within the extraction apparatus, make it essential that theoretical air velocities are multiplied by factors of 10 or more when extraction systems are installed or used.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

APPEARANCE

■ Material is hygroscopic, absorbs moisture from surrounding air.
Small white crystals, granules, or flakes. No odour. Soluble in water. Solution in water accompanied by evolution of heat. Soluble in alcohol.

PHYSICAL PROPERTIES

Solid.
Mixes with water.

 

StateDivided solidMolecular Weight110.99
Melting Range (ºC)772ViscosityNot Applicable
Boiling Range (ºC)>1600Solubility in water (g/L)Miscible
Flash Point (ºC)Not ApplicablepH (1% solution)Not available.
Decomposition Temp (ºC)Not available.pH (as supplied)Not applicable
Autoignition Temp (ºC)Not applicableVapour Pressure (kPa)Negligible
Upper Explosive Limit (%)Not applicableSpecific Gravity (water=1)2.15
Lower Explosive Limit (%)Not applicableRelative Vapour Density (air=1)Not applicable.
Volatile Component (%vol)NilEvaporation RateNot Applicable

 

StateDivided solidMolecular Weight110.99
Melting Range (ºC)772ViscosityNot Applicable
Boiling Range (ºC)>1600Solubility in water (g/L)Miscible
Flash Point (ºC)Not ApplicablepH (1% solution)Not available.
Decomposition Temp (ºC)Not available.pH (as supplied)Not applicable
Autoignition Temp (ºC)Not applicableVapour Pressure (kPa)Negligible
Upper Explosive Limit (%)Not applicableSpecific Gravity (water=1)2.15
Lower Explosive Limit (%)Not applicableRelative Vapour Density (air=1)Not applicable.
Volatile Component (%vol)NilEvaporation RateNot Applicable

Section 10 - STABILITY AND REACTIVITY

CONDITIONS CONTRIBUTING TO INSTABILITY

· Presence of incompatible materials.
· Product is considered stable.
· Hazardous polymerisation will not occur.

For incompatible materials - refer to Section 7 - Handling and Storage.

Section 11 - TOXICOLOGICAL INFORMATION

POTENTIAL HEALTH EFFECTS

ACUTE HEALTH EFFECTS

SWALLOWED

■ Accidental ingestion of the material may be harmful; animal experiments indicate that ingestion of less than 150 gram may be fatal or may produce serious damage to
the health of the individual.

EYE

■ There is evidence that material may produce eye irritation in some persons and produce eye damage 24 hours or more after instillation. Severe inflammation may be
expected with pain. There may be damage to the cornea. Unless treatment is prompt and adequate there may be permanent loss of vision. Conjunctivitis can occur
following repeated exposure.

SKIN

■ Skin contact is not thought to produce harmful health effects (as classified under EC Directives using animal models). Systemic harm, however, has been identified
following exposure of animals by at least one other route and the material may still produce health damage following entry through wounds, lesions or abrasions. Good
hygiene practice requires that exposure be kept to a minimum and that suitable gloves be used in an occupational setting.
Repeated exposure may cause skin cracking, flaking or drying following normal handling and use.
Open cuts, abraded or irritated skin should not be exposed to this material.
Solution of material in moisture on the skin, or perspiration, may increase irritant effects.
Entry into the blood- stream, through, for example, cuts, abrasions or lesions, may produce systemic injury with harmful effects. Examine the skin prior to the use
of the material and ensure that any external damage is suitably protected.

INHALED

■ The material is not thought to produce either adverse health effects or irritation of the respiratory tract following inhalation (as classified by EC Directives
using animal models). Nevertheless, adverse systemic effects have been produced following exposure of animals by at least one other route and good hygiene practice
requires that exposure be kept to a minimum and that suitable control measures be used in an occupational setting.
Persons with impaired respiratory function, airway diseases and conditions such as emphysema or chronic bronchitis, may incur further disability if excessive
concentrations of particulate are inhaled.
If prior damage to the circulatory or nervous systems has occurred or if kidney damage has been sustained, proper screenings should be conducted on individuals who
may be exposed to further risk if handling and use of the material result
in excessive exposures.

CHRONIC HEALTH EFFECTS

■ Prolonged or repeated skin contact may cause drying with cracking, irritation and possible dermatitis following.
Substance accumulation, in the human body, may occur and may cause some concern following repeated or long- term occupational exposure.
Long term exposure to high dust concentrations may cause changes in lung function i.e. pneumoconiosis; caused by particles less than 0.5 micron penetrating and
remaining in the lung. Prime symptom is breathlessness; lung shadows show on X- ray.
High blood concentrations of calcium ion may give rise to vasodilation and depress cardiac function leading to hypotension and syncope. Calcium ions enhance the
effects of digitalis on the heart and may precipitate digitalis intoxication. Calcium salts also reduce the absorption of tetracyclines
In neonates calcification of soft- tissue has been observed following therapeutic administration.

TOXICITY AND IRRITATION

CALCIUM CHLORIDE:
■ unless otherwise specified data extracted from RTECS - Register of Toxic Effects of Chemical Substances.
TOXICITY IRRITATION
Oral (rat) LD50: 1000 mg/kg Skin (unknown): moderate*
Subcutaneous (Dog) LDLo: 274 mg/kg Eye (unknown): severe* [ICI]
Intravenous (Dog) LDLo: 274 mg/kg
Subcutaneous (Cat) LDLo: 249 mg/kg
Intravenous (Cat) LDLo: 249 mg/kg
Oral (Rabbit) LDLo: 1384 mg/kg
Subcutaneous (Rabbit) LDLo: 472 mg/kg
Intravenous (Rabbit) LDLo: 274 mg/kg
Intravenous (Guinea pig) LDLo: 150 mg/kg
Oral (Rabbit) LD50: 1384 mg/kg
Intraperitoneal (Mouse) LD50: 600 mg/kg
Intravenous (Dog) TDLo: 39.95 mg/kg
Intraperitoneal (Mouse) LD: 399.5 mg/kg
Intravenous (Rat) TDLo: 300 mg/kg
Intravenous (Human) TDLo: 20 mg/kg
Intraperitoneal (Rat) LD50: 264 mg/kg
Subcutaneous (Rat) LD50: 2630 mg/kg
Intravenous (Rat) LDLo: 161 mg/kg
Oral (Mouse) LD50: 1940 mg/kg
Intraperitoneal (Mouse) LD50: 210 mg/kg
Subcutaneous (Mouse) LD50: 823 mg/kg
Intravenous (Mouse) LD50: 42 mg/kg
■ The material may produce severe irritation to the eye causing pronounced inflammation. Repeated or prolonged exposure to irritants may produce conjunctivitis. The material may cause skin irritation after prolonged or repeated exposure and may produce on contact skin redness, swelling, the production of vesicles, scaling and thickening of the skin. for calcium: Toxicity from calcium is not common because the gastrointestinal tract normally limits the amount of calcium absorbed. Therefore, short- term intake of large amounts of calcium does not generally produce any ill effects aside from constipation and an increased risk of kidney stones . However, more severe toxicity can occur when excess calcium is ingested over long periods, or when calcium is combined with increased amounts of vitamin D, which increases calcium absorption. Calcium toxicity is also sometimes found after excessive intravenous administration of calcium. Toxicity is manifested by abnormal deposition of calcium in tissues and by elevated blood calcium levels (hypercalcaemia). However, hypercalcaemia is often due to other causes, such as abnormally high amounts of parathyroid hormone (PTH). Usually, under these circumstances, bone density is lost and the resulting hypercalcaemia can cause kidney stones and abdominal pain. Some cancers can also cause hypercalcaemia, either by secreting abnormal proteins that act like PTH or by invading and killing bone cells causing them to release calcium. Very high levels of calcium can result in appetite loss, nausea , vomiting, abdominal pain, confusion, seizures, and even coma. for calcium chloride: Acute toxicity: The acute oral toxicity of calcium chloride is low: LD50 in mice is 1940- 2045 mg/kg bw, 3798- 4179 mg/kg bw in rats, and 500- 1000 mg/kg bw in rabbits. The acute oral toxicity is attributed to the severe irritating property of the original substance or its high- concentration solutions to the gastrointestinal tract. In humans, however, acute oral toxicity is rare because large single doses induce nausea and vomiting. The dermal acute toxicity is negligible: LD50 in rabbits >5000 mg/kg bw. No significant change was found by gross necropsy examination except skin lesions at or near the site of administration. Hypercalcaemia may occur only when there exists other factors that alter calcium homeostasis, such as renal inefficiency and primary hyperthyroidism. Irritation/corrosiveness studies conducted under OECD test guidelines indicate that calcium chloride is not/slightly irritating to skin but severely irritating to eyes of rabbits. Prolonged exposure and application of moistened material or concentrated solutions resulted in considerable skin irritation, however. Irritating effect of the substance was observed in human skin injuries caused by incidental contact with the substance or its high- concentration solutions. Repeat dose toxicity: A limited oral repeated dose toxicity study shows no adverse effect of calcium chloride on rats fed on 1000- 2000 mg/kg bw/day for 12 months. Calcium and chloride are both essential nutrients for humans and a daily intake of more than 1000 mg each of the ions is recommended. The establishment of the ADI for calcium chloride has not been deemed necessary by JECFA (Joint FAO/WHO Expert Committee on Food Additives) Genotoxicity: Genetic toxicity of calcium chloride was negative in the bacterial mutation tests and the mammalian chromosome aberration test. Reproductive and developmental toxicity: No reproductive toxicity study has been reported. A developmental toxicity study equivalent to an OECD Guideline study, on the other hand, reveals no toxic effects on dams or foetuses at doses up to 189 mg/kg bw/day (mice), 176 mg/kg bw/day (rats) and 169 mg/kg bw/day (rabbits).

 

 

Section 12 - ECOLOGICAL INFORMATION

CALCIUM CHLORIDE:
Fish LC50 (96hr.) (mg/l): 
8.4 (24hr)
■ for calcium chloride: Environmental fate: Calcium chlorides vapour pressure is negligible and its water solubility is 745 g/L at 20 deg C. Calcium chloride is readily dissociated into calcium and chloride ions in water. These physico- chemical properties indicate that calcium chloride released into the environment is distributed into the water compartment in the form of calcium and chloride ions. Ecotoxicity: Fish LC50 (96 h): Pimephales promelas 4630 mg/l Algae EC50 (72 h): Selenastrum capricornutum 2900 mg/l Daphnia magna EC50 (48 h): 1062 mg/l The chronic toxicity study with Daphnia magna shows that a 16% impairment of reproduction (EC16) is caused at the concentration of 320 mg/L. The 72- hour EC20 for Selenastrum capricornutum determined by the OECD TG 201 study is 1000 mg/L. All the data compiled on the acute and chronic toxicity are greater than 100 mg/L. Although inorganic chloride ions are not normally considered toxic they can exist in effluents at acutely toxic levels (chloride >3000 mg/l). The resulting salinity can exceed the tolerances of most freshwater organisms. Inorganic chlorine eventually finds its way into the aqueous compartment and as such is bioavailable. Incidental exposure to inorganic chloride may occur in occupational settings where chemicals management policies are improperly applied. The toxicity of chloride salts depends on the counter- ion (cation) present; that of chloride itself is unknown. Chloride toxicity has not been observed in humans except in the special case of impaired sodium chloride metabolism, e.g. in congestive heart failure. Healthy individuals can tolerate the intake of large quantities of chloride provided that there is a concomitant intake of fresh water. Although excessive intake of drinking- water containing sodium chloride at concentrations above 2.5 g/litre has been reported to produce hypertension, this effect is believed to be related to the sodium ion concentration. Chloride concentrations in excess of about 250 mg/litre can give rise to detectable taste in water, but the threshold depends upon the associated cations. Consumers can, however, become accustomed to concentrations in excess of 250 mg/litre. No health- based guideline value is proposed for chloride in drinking- water. In humans, 88% of chloride is extracellular and contributes to the osmotic activity of body fluids. The electrolyte balance in the body is maintained by adjusting total dietary intake and by excretion via the kidneys and gastrointestinal tract. Chloride is almost completely absorbed in normal individuals, mostly from the proximal half of the small intestine. Normal fluid loss amounts to about 1.5- 2 liters/day, together with about 4 g of chloride per day. Most (90 - 95%) is excreted in the urine, with minor amounts in faeces (4- 8%) and sweat (2%). Chloride increases the electrical conductivity of water and thus increases its corrosivity. In metal pipes, chloride reacts with metal ions to form soluble salts thus increasing levels of metals in drinking- water. In lead pipes, a protective oxide layer is built up, but chloride enhances galvanic corrosion. It can also increase the rate of pitting corrosion of metal pipes. DO NOT discharge into sewer or waterways.

Ecotoxicity

IngredientPersistence: Water/SoilPersistence: AirBioaccumulationMobility
calcium chlorideNo Data AvailableNo Data AvailableLOW

 

Section 13 - DISPOSAL CONSIDERATIONS

· Containers may still present a chemical hazard/ danger when empty.
· Return to supplier for reuse/ recycling if possible.
Otherwise:
· If container can not be cleaned sufficiently well to ensure that residuals do not remain or if the container cannot be used to store the same product, then puncture containers, to prevent re-use, and bury at an authorised landfill.
· Where possible retain label warnings and MSDS and observe all notices pertaining to the product.
Legislation addressing waste disposal requirements may differ by country, state and/ or territory. Each user must refer to laws operating in their area. In some areas, certain wastes must be tracked.
A Hierarchy of Controls seems to be common - the user should investigate:
· Reduction
· Reuse
· Recycling
· Disposal (if all else fails)
This material may be recycled if unused, or if it has not been contaminated so as to make it unsuitable for its intended use. Shelf life considerations should also be applied in making decisions of this type. Note that properties of a material may change in use, and recycling or reuse may not always be appropriate.
· DO NOT allow wash water from cleaning or process equipment to enter drains.
· It may be necessary to collect all wash water for treatment before disposal.
· In all cases disposal to sewer may be subject to local laws and regulations and these should be considered first.
· Where in doubt contact the responsible authority.
· Recycle wherever possible or consult manufacturer for recycling options.
· Consult State Land Waste Management Authority for disposal.
· Bury residue in an authorised landfill.
· Recycle containers if possible, or dispose of in an authorised landfill.

Section 14 - TRANSPORTATION INFORMATION

HAZCHEM:

None (ADG7)
NOT REGULATED FOR TRANSPORT OF DANGEROUS GOODS: ADG7, UN, IATA, IMDG

Section 15 - REGULATORY INFORMATION

POISONS SCHEDULE None

REGULATIONS

calcium chloride (CAS: 10043-52-4) is found on the following regulatory lists;

"Australia Hazardous Substances","Australia High Volume Industrial Chemical List (HVICL)","Australia Inventory of Chemical Substances (AICS)","CODEX General Standard for Food Additives (GSFA) - Additives Permitted for Use in Food in General, Unless Otherwise Specified, in Accordance with GMP","IMO Provisional Categorization of Liquid Substances - List 3: (Trade-named) mixtures containing at least 99% by weight of components already assessed by IMO, presenting safety hazards","International Council of Chemical Associations (ICCA) - High Production Volume List"

Section 16 - OTHER INFORMATION

CONTACT POINT

Paul Milward-Bason
17 Grandview Parade
Moolap 3221
Victoria Australia

 

MSDS SECTION CHANGES

The following table displays the version number of and date on which each section was last changed.

Section Name        Version  Date             Section Name        Version  Date             Section Name        Version  Date
Advice to Doctor    4        27- May- 2009    Handling Procedure  4        27- May- 2009    Physical            4        27- May- 2009
                                                                                            Properties
First Aid (eye)     4        27- May- 2009    Storage (storage    4        27- May- 2009    Instability         4        27- May- 2009
                                              incompatibility)                              Condition
First Aid           4        27- May- 2009    Storage (storage    4        27- May- 2009    Acute Health (eye)  4        27- May- 2009
(inhaled)                                     requirement)
First Aid (skin)    4        27- May- 2009    Storage (suitable   4        27- May- 2009    Acute Health        4        27- May- 2009
                                              container)                                    (inhaled)
First Aid           4        27- May- 2009    Engineering         4        27- May- 2009    Acute Health        4        27- May- 2009
(swallowed)                                   Control                                       (skin)
Fire Fighter        4        27- May- 2009    Exposure Standard   4        27- May- 2009    Acute Health        4        27- May- 2009
(extinguishing                                                                              (swallowed)
media)
Fire Fighter (fire  4        27- May- 2009    Personal            4        27- May- 2009    Chronic Health      4        27- May- 2009
fighting)                                     Protection (eye)
Fire Fighter (fire  4        27- May- 2009    Personal            4        27- May- 2009    Toxicity and        4        27- May- 2009
incompatibility)                              Protection                                    Irritation (Other)
                                              (hands/feet)
Fire Fighter        4        27- May- 2009    Personal            4        27- May- 2009    Environmental       4        27- May- 2009
(fire/explosion                               Protection (other)
hazard)
Spills (major)      4        27- May- 2009    Appearance          4        27- May- 2009    Disposal            4        27- May- 2009
Spills (minor)      4        27- May- 2009

 

■ Classification of the preparation and its individual components has drawn on official and authoritative sources as well as independent review by the Chemwatch Classification committee using available literature references.
A list of reference resources used to assist the committee may be found at:
www.chemwatch.net/references.

 

■ The (M)SDS is a Hazard Communication tool and should be used to assist in the Risk Assessment. Many factors determine whether the reported Hazards are Risks in the workplace or other settings. Risks may be determined by reference to Exposures Scenarios. Scale of use, frequency of use and current or available engineering controls must be considered.

 

 

This document is copyright. Apart from any fair dealing for the purposes of private study, research, review or
criticism, as permitted under the Copyright Act, no part may be reproduced by any process without written
permission from CHEMWATCH. TEL (+61 3) 9572 4700.

 

Issue Date: 17-Jul-2011

Print Date: 17-Feb-2012

 

 

This is the end of the MSDS.